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Isolation of centrolobular and perilobular hepatocytes after phenobarbital treatment

Daily phenobarbital (PB) injections, on 3-7 consecutive days, induce an intense proliferation of smooth endoplasmic reticulum (ER) associated with a decrease of the glucose-6-phosphatase activity. This situation first affects the centrolobular hepatocytes, enhancing the degree of liver lobule hetero...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1975
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2109530/
https://ncbi.nlm.nih.gov/pubmed/167029
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