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Nucleolar necklaces in chick embryo fibroblast cells. I. Formation of necklaces by dichlororibobenzimidazole and other adenosine analogues that decrease RNA synthesis and degrade preribosomes

A number of chemicals, mostly adenosine analogues, cause the nucleolus of the chick embryo fibroblast to lose material and unravel over a period of several hours into beaded strands termed nucleolar necklaces (NN). The results of analyses of the fibroblasts, treated with the NN- forming chemical dic...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1975
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2109428/
https://ncbi.nlm.nih.gov/pubmed/1168650
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