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DETERMINATION OF RATES OF DNA SYNTHESIS IN CULTURED MAMMALIAN CELL POPULATIONS

In cultures of a murine mastocytoma, endogenous synthesis of thymidine phosphates, as determined by the incorporation of [(3)H]deoxyuridine into DNA, was reduced within 15 min to less than 3% of control values by the addition of amethopterin (10 µM) in combination with hypoxanthine and glycine. If [...

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Detalhes bibliográficos
Main Authors: Siegers, M. P., Schaer, J. C., Hirsiger, H., Schindler, R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2109404/
https://ncbi.nlm.nih.gov/pubmed/4214821
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