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CYTOCHALASIN B : VI. Competitive Inhibition of Nucleoside Transport by Cultured Novikoff Rat Hepatoma Cells

Cytochalasin B competitively inhibits the transport of uridine and thymidine by Novikoff rat hepatoma cells growing in suspension culture with apparent K(i)'s of 2 and 6 µM, respectively, but has no effect on the intracellular phosphorylation of the nucleosides. Choline transport is not affecte...

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Bibliographic Details
Main Authors: Plagemann, Peter G. W., Estensen, Richard D.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1972
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2108743/
https://ncbi.nlm.nih.gov/pubmed/4347250
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