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THE SELECTIVE INTERRUPTION OF NUCLEOLAR RNA SYNTHESIS IN HELA CELLS BY CORDYCEPIN

Cordycepin is an analogue of adenosine lacking the 3'-OH. When incorporated into a growing RNA molecule, cordycepin prevents further elongation, thus producing a prematurely terminated RNA molecule. When HeLa cells are exposed to low concentrations of cordycepin, DNA and protein synthesis are u...

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Bibliographic Details
Main Authors: Siev, Moshe, Weinberg, Robert, Penman, Sheldon
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1969
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2107749/
https://ncbi.nlm.nih.gov/pubmed/5783871
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