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Mini-P1 plasmid partitioning: excess ParB protein destabilizes plasmids containing the centromere parS.

The partition system of the unit-copy plasmid P1 consists of two proteins, the parA and parB gene products, and a cis-acting site, parS. Production of high levels of the P1 ParB protein, from an external promoter on a high-copy-number vector, inhibits the propagation of lambda-mini-P1 prophages and...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Hovedforfatter: Funnell, B E
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1988
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC210747/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2962991/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.170.2.954-960.1988
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