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THE PENETRATION OF REOVIRUS RNA AND INITIATION OF ITS GENETIC FUNCTION IN L-STRAIN FIBROBLASTS

Reovirus type 3 is phagocytized by L cells and rapidly sequestered inside lysosomes. Hydrolases within these organelles are capable of stripping the viral coat proteins, but they fail to degrade the double-stranded RNA genome. These observations support the view that sojourn of reovirus in lysosomes...

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Detalhes bibliográficos
Main Authors: Silverstein, Samuel C., Dales, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1968
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2107329/
https://ncbi.nlm.nih.gov/pubmed/19806702
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