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RAPID RELEASE OF THE ZYMOGEN GRANULE PROTEIN BY OSMIUM TETROXIDE AND ITS RETENTION DURING FIXATION BY GLUTARALDEHYDE

Fixation by osmium tetroxide and glutaraldehyde of zymogen granules isolated from rat parotid and pancreas was investigated. Protein determinations showed that osmium tetroxide caused rapid release of most of the soluble protein of the granule during fixation in buffered isotonic sucrose. Such granu...

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Detalhes bibliográficos
Main Authors: Amsterdam, Abraham, Schramm, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1966
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2106903/
https://ncbi.nlm.nih.gov/pubmed/5335826
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