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ON THE MECHANISM OF DRUG HYDROXYLATION IN RAT LIVER MICROSOMES

The TPNH- and O(2)-dependent drug hydroxylation system of liver microsomes has been studied using normal rats and rats in which the drug-hydroxylating activity has been enhanced by repeated injections of phenobarbital. The oxidative demethylation of aminopyrine is employed as an assay. Optimal condi...

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Hlavní autor: Orrenius, Sten
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1965
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2106795/
https://ncbi.nlm.nih.gov/pubmed/19866674
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