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PHENOBARBITAL-INDUCED SYNTHESIS OF THE MICROSOMAL DRUG-METABOLIZING ENZYME SYSTEM AND ITS RELATIONSHIP TO THE PROLIFERATION OF ENDOPLASMIC MEMBRANES : A Morphological and Biochemical Study

Liver microsomes, isolated from rats which had been treated with phenobarbital in vivo, were found to exhibit increased activities of oxidative demethylation and TPNH-cytochrome c reductase and an increased amount of CO-binding pigment. Simultaneous administration of actinomycin D or puromycin aboli...

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Hlavní autoři: Orrenius, Sten, Ericsson, Jan L. E., Ernster, Lars
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1965
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2106691/
https://ncbi.nlm.nih.gov/pubmed/4378769
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