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Overexpression of angiotensin AT(1) receptor transgene in the mouse myocardium produces a lethal phenotype associated with myocyte hyperplasia and heart block

Previous studies have suggested that angiotensin II (Ang II) modulates cardiac contractility, rhythm, metabolism, and structure. However, it is unclear whether the cardiac effects are due to direct actions of Ang II on the myocardium or if they are due to secondary effects mediated through the hemod...

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Autors principals: Hein, Lutz, Stevens, Mary E., Barsh, Gregory S., Pratt, Richard E., Kobilka, Brian K., Dzau, Victor J.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC21060/
https://ncbi.nlm.nih.gov/pubmed/9177228
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