High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: Inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers

The expression of cyclin-dependent kinase inhibitor p27(kip1) in human tumors and normal tissues was investigated using a panel of novel anti-p27(kip1) mAbs. An inverse correlation between expression of p27(kip1) and cell proliferation was generally observed after analyzing its expression in 25 diff...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Fredersdorf, Steffen, Burns, Jorges, Milne, Alistair M., Packham, Graham, Fallis, Lynn, Gillett, Cheryl E., Royds, Janice A., Peston, David, Hall, Peter A., Hanby, Andrew M., Barnes, Diana M., Shousha, Sami, O’Hare, Mike J., Lu, Xin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21058/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9177226/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.12.6380
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