Erythromycin-induced ribosome stall in the ermA leader: a barricade to 5'-to-3' nucleolytic cleavage of the ermA transcript.

The Staphylococcus aureus ermA gene, whose product confers resistance to the macrolide-lincosamide-streptogramin B family of antibiotics, is induced at the level of translation by nanomolar concentrations of erythromycin. Erythromycin also specifically stabilizes ermA transcripts, and the induced st...

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Veröffentlicht in:	J Bacteriol
Hauptverfasser:	Sandler, P, Weisblum, B
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC210563/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2592348/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.171.12.6680-6688.1989
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