Significant linkage to chromosome 12q24.32–q24.33 and identification of SFRS8 as a possible asthma susceptibility gene

BACKGROUND: Asthma is a complex genetic disorder. Many studies have suggested that chromosome 12q harbours a susceptibility gene for asthma and atopy. Linkage on chromosome 12q24.21–q24.33 was investigated in 167 Danish families with asthma. METHODS: A two step procedure was used: (1) a genome‐wide...

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Autores principales: Brasch‐Andersen, C, Tan, Q, Børglum, A D, Haagerup, A, Larsen, T R, Vestbo, J, Kruse, T A
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Group 2006
Materias:
Asthma
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2104763/
https://ncbi.nlm.nih.gov/pubmed/16738036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2005.055475
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