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Drosophila drop-dead mutations accelerate the time course of age-related markers

Mutations of the drop-dead gene in Drosophila melanogaster lead to striking early death of the adult animal. At different times, after emergence from the pupa, individual flies begin to stagger and, shortly thereafter, die. Anatomical examination reveals gross neuropathological lesions in the brain....

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Rogina, Blanka, Benzer, Seymour, Helfand, Stephen L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21044/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9177212/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.12.6303
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