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Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins

Glial cell line-derived neurotrophic factor (GDNF)-dependent activation of the tyrosine kinase receptor RET is necessary for kidney and enteric neuron development, and mutations in RET are associated with human diseases. Activation of RET by GDNF has been shown to require an accessory component, GDN...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Sanicola, M., Hession, C., Worley, D., Carmillo, P., Ehrenfels, C., Walus, L., Robinson, S., Jaworski, G., Wei, H., Tizard, R., Whitty, A., Pepinsky, R. B., Cate, R. L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1997
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21033/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9177201/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.12.6238
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