Heterologous expression of the alpha-amylase inhibitor gene cloned from an amplified genomic sequence of Streptomyces tendae.

The coding region for a secreted proteinaceous inhibitor of the human alpha-amylase (tendamistat; HOE 467) was identified by using a synthetic oligonucleotide probe. The gene is part of a 37-kilobase amplified genomic sequence found in an overproducing mutant of Streptomyces tendae. After subcloning...

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Библиографические подробности

Опубликовано в::	J Bacteriol
Главные авторы:	Koller, K P, Riess, G
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1989
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC210302/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2788646/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.171.9.4953-4957.1989
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