Methylation of 23S rRNA caused by tlrA (ermSF), a tylosin resistance determinant from Streptomyces fradiae.

Ribosomes from Streptomyces griseofuscus expressing tlrA, a resistance gene isolated from the tylosin producer Streptomyces fradiae, are resistant to macrolide and lincosamide antibiotics in vitro. The tlrA product was found to be a methylase that introduces two methyl groups into a single base with...

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Xehetasun bibliografikoak

Argitaratua izan da:	J Bacteriol
Egile Nagusiak:	Zalacain, M, Cundliffe, E
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 1989
Gaiak:	Research Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC210198/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2753855/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.171.8.4254-4260.1989
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