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Binding of the Citrobacter freundii AmpR regulator to a single DNA site provides both autoregulation and activation of the inducible ampC beta-lactamase gene.

Citrobacter freundii encodes an inducible chromosomal beta-lactamase. Induction requires the product of the ampR gene, which is transcribed in the opposite orientation from the ampC beta-lactamase gene. We show here that the AmpR protein acts as a transcriptional activator by binding to a DNA region...

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Bibliografische Detailangaben
Veröffentlicht in:J Bacteriol
Hauptverfasser: Lindquist, S, Lindberg, F, Normark, S
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1989
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC210120/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2786868/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.171.7.3746-3753.1989
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