Binding of the Citrobacter freundii AmpR regulator to a single DNA site provides both autoregulation and activation of the inducible ampC beta-lactamase gene.

Citrobacter freundii encodes an inducible chromosomal beta-lactamase. Induction requires the product of the ampR gene, which is transcribed in the opposite orientation from the ampC beta-lactamase gene. We show here that the AmpR protein acts as a transcriptional activator by binding to a DNA region...

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Detalles Bibliográficos
Main Authors: Lindquist, S, Lindberg, F, Normark, S
Formato: Artigo
Idioma:Inglês
Publicado: 1989
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC210120/
https://ncbi.nlm.nih.gov/pubmed/2786868
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