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IL-7 receptor deficient SCID with a unique intronic mutation and post-transplant autoimmunity due to chronic GVHD

Severe combined immunodeficiency (SCID) may result from a variety of genetic defects that impair the development of T cells. Signaling mediated by the cytokine interleukin-7 is essential for the differentiation of T cells from lymphoid progenitors, and mutations of either the interleukin-7 receptor...

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Autors principals: Butte, Manish J., Haines, Charles, Bonilla, Francisco A., Puck, Jennifer
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2100404/
https://ncbi.nlm.nih.gov/pubmed/17827065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2007.06.007
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