Assembly of a rod-shaped chimera of a trimeric GCN4 zipper and the HIV-1 gp41 ectodomain expressed in Escherichia coli

The HIV-1 envelope subunit gp41 plays a role in viral entry by initiating fusion of the viral and cellular membranes. A chimeric molecule was constructed centered on the ectodomain of gp41 without the fusion peptide, with a trimeric isoleucine zipper derived from GCN4 (pIIGCN4) on the N terminus and...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Weissenhorn, Winfried, Calder, Lesley J., Dessen, Andréa, Laue, Tom, Skehel, John J., Wiley, Don C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21001/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9177169/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.12.6065
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