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Tumor microvasculature and microenvironment: Targets for anti-angiogenesis and normalization

A solid tumor forms an organ-like entity comprised of neoplastic cells and non-transformed host stromal cells embedded in an extracellular matrix. Similar to normal tissues, blood vessels nourish cells residing in tumors. However, unlike normal blood vessels, tumor vasculature has abnormal organizat...

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Bibliographic Details
Main Authors: Fukumura, Dai, Jain., Rakesh K.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2100036/
https://ncbi.nlm.nih.gov/pubmed/17560615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mvr.2007.05.003
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