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Tip60 Histone Acetyltransferase Acts as a Negative Regulator of Notch1 Signaling by Means of Acetylation

The Notch signaling pathway appears to perform an important function in a wide variety of organisms and cell types. In our present study, we provide evidence that UV irradiation-induced Tip60 proteins reduced Notch1 activity to a marked degree. Accumulated UV irradiation-induced Tip60 suppresses Not...

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Detalhes bibliográficos
Main Authors: Kim, Mi-Yeon, Ann, Eun-Jung, Kim, Jin-Young, Mo, Jung-Soon, Park, Ji-Hye, Kim, Sun-Yee, Seo, Mi-Sun, Park, Hee-Sae
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099611/
https://ncbi.nlm.nih.gov/pubmed/17636029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01515-06
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