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Activation of Cdc2 Contributes to Apoptosis in HPV E6 Expressing Human Keratinocytes in Response to Therapeutic Agents

Infection with human papillomaviruses (HPV) is strongly associated with the development of cervical cancer. The HPV E6 oncogene induces apoptosis in cervical cancer precursor lesions but the mechanism is poorly understood. While it is expected that inactivation of p53 by E6 should lead to a reductio...

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Bibliografiske detaljer
Main Authors: Liu, Zhi-Guo, Zhao, Li-Na, Liu, Ying-Wang, Li, Ting-Ting, Fan, Dai-Ming, Chen, Jason J
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099577/
https://ncbi.nlm.nih.gov/pubmed/17936297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.09.031
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