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Analysis of nanopore detector measurements using Machine-Learning methods, with application to single-molecule kinetic analysis

BACKGROUND: A nanopore detector has a nanometer-scale trans-membrane channel across which a potential difference is established, resulting in an ionic current through the channel in the pA-nA range. A distinctive channel current blockade signal is created as individually "captured" DNA mol...

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Main Authors: Landry, Matthew, Winters-Hilt, Stephen
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099480/
https://ncbi.nlm.nih.gov/pubmed/18047711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-S7-S12
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