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The large-conductance Ca(2+)-activated K(+) channel is essential for innate immunity

Neutrophil leukocytes have a pivotal function in innate immunity. Dogma dictates that the lethal blow is delivered to microbes by reactive oxygen species (ROS) and halogens1,2, products of the NADPH oxidase, whose impairment causes immunodeficiency. However, recent evidence indicates that the microb...

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Detalles Bibliográficos
Main Authors: Ahluwalia, Jatinder, Tinker, Andrew, Clapp, Lucie H., Duchen, Michael R., Abramov, Andrey Y., Pope, Simon, Nobles, Muriel, Segal, Anthony W.
Formato: Artigo
Idioma:Inglês
Publicado: 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099462/
https://ncbi.nlm.nih.gov/pubmed/14985765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature02356
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