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Ribosomal Slowdown Mediates Translational Arrest during Cellular Division

Global mRNA translation is transiently inhibited during cellular division. We demonstrate that mitotic cells contain heavy polysomes, but these are significantly less translationally active than polysomes in cycling cells. Several observations indicate that mitotic translational attenuation occurs d...

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Detalhes bibliográficos
Main Authors: Sivan, Gilad, Kedersha, Nancy, Elroy-Stein, Orna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099241/
https://ncbi.nlm.nih.gov/pubmed/17664278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00798-07
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