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Rpn10-Mediated Degradation of Ubiquitinated Proteins Is Essential for Mouse Development

Rpn10 is a subunit of the 26S proteasome that recognizes polyubiquitinated proteins. The importance of Rpn10 in ubiquitin-mediated proteolysis is debatable, since a deficiency of Rpn10 causes different phenotypes in different organisms. To date, the role of mammalian Rpn10 has not been examined gene...

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Bibliografske podrobnosti
Main Authors: Hamazaki, Jun, Sasaki, Katsuhiro, Kawahara, Hiroyuki, Hisanaga, Shin-ichi, Tanaka, Keiji, Murata, Shigeo
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099239/
https://ncbi.nlm.nih.gov/pubmed/17646385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00509-07
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