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Wild-Type NRas and KRas Perform Distinct Functions during Transformation

The ras proto-oncogenes, of which there are four isoforms, are molecular switches that function in signal transduction pathways to control cell differentiation, proliferation, and survival. How the Ras isoforms orchestrate cellular processes that affect behavior is poorly understood. Further, why ce...

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Detalhes bibliográficos
Main Authors: Fotiadou, Poppy P., Takahashi, Chiaki, Rajabi, Hasan N., Ewen, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099215/
https://ncbi.nlm.nih.gov/pubmed/17636015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00234-07
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