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Bub1 Kinase Targets Sgo1 to Ensure Efficient Chromosome Biorientation in Budding Yeast Mitosis

During cell division all chromosomes must be segregated accurately to each daughter cell. Errors in this process give rise to aneuploidy, which leads to birth defects and is implicated in cancer progression. The spindle checkpoint is a surveillance mechanism that ensures high fidelity of chromosome...

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Detalhes bibliográficos
Main Authors: Fernius, Josefin, Hardwick, Kevin G
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2098806/
https://ncbi.nlm.nih.gov/pubmed/18081426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030213
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