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Formation of supercoiling domains in plasmid pBR322.

Twin domains of positive and negative supercoiling are thought to form in DNA molecules whenever free rotation of a transcription complex around the DNA helix is impeded. Evidence for these domains has come from findings with Escherichia coli strains that are deficient in DNA topoisomerase I (top mu...

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Detalles Bibliográficos
Autores principales: Lodge, J K, Kazic, T, Berg, D E
Formato: Artigo
Lenguaje:Inglês
Publicado: 1989
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC209875/
https://ncbi.nlm.nih.gov/pubmed/2649489
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