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Comparison of the Pharmacological Effects of a Novel Selective Androgen Receptor Modulator, the 5α-Reductase Inhibitor Finasteride, and the Antiandrogen Hydroxyflutamide in Intact Rats: New Approach for Benign Prostate Hyperplasia

Tissue-selective androgen receptor modulators (SARMs) demonstrate tissue selectivity in both castrated and intact male rats, behaving as partial agonists in androgenic tissues (i.e. prostate and seminal vesicle), but full agonists in anabolic tissues (i.e. levator ani muscle). The partial agonist ac...

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Detalhes bibliográficos
Main Authors: Gao, Wenqing, Kearbey, Jeffrey D., Nair, Vipin A., Chung, Kiwon, Parlow, A. F., Miller, Duane D., Dalton, James T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2098692/
https://ncbi.nlm.nih.gov/pubmed/15308613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2004-0627
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