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Deletion hot spots in chimeric Escherichia coli plasmids.

Deletions form frequently in chimeric plasmids composed of M13mp2, pBR322, and pC194 (B. Michel and S. D. Ehrlich, Proc. Natl. Acad. Sci. USA 83:3386-3390, 1986). They are generated by joining of the nucleotide neighboring the nick site in the M13 replication origin to a nonadjacent nucleotide. This...

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Published in:J Bacteriol
Main Authors: Michel, B, D'Alençon, E, Ehrlich, S D
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1989
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209831/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2649476/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.171.4.1846-1853.1989
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