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Nucleotide sequence and transcriptional analysis of the Streptomyces griseus gene (afsA) responsible for A-factor biosynthesis.

The nucleotide sequence of the Streptomyces griseus afsA gene, possibly encoding a key enzyme for A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) biosynthesis, was determined. The translational initiation codon was identified by introducing out-of-frame mutations at appropriate positi...

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Main Authors: Horinouchi, S, Suzuki, H, Nishiyama, M, Beppu, T
Format: Artigo
Jezik:Inglês
Izdano: 1989
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC209724/
https://ncbi.nlm.nih.gov/pubmed/2492509
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