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P2 receptors in macrophage fusion and osteoclast formation

Cells of the mononuclear phagocyte lineage fuse to form multinucleated giant cells and osteoclasts. Several lines of evidence suggest that P2 receptors, in particular P2X(7), are involved in this process, although P2X(7) is not absolutely required for fusion because P2X(7)-null mice form multinuclea...

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Detalhes bibliográficos
Main Authors: Steinberg, Thomas H., Hiken, Jeffrey F.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096767/
https://ncbi.nlm.nih.gov/pubmed/18404418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-006-9036-9
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