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Kalirin/Trio Rho Guanine Nucleotide Exchange Factors Regulate a Novel Step in Secretory Granule Maturation

The molecular mechanisms involved in the maturation of secretory granules, organelles that store hormones and neuropeptides, are poorly understood. As granule content proteins are processed, the composition of granule membranes changes, yielding constitutive-like secretion of immature content protei...

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Autors principals: Ferraro, Francesco, Ma, Xin-Ming, Sobota, Jacqueline A., Eipper, Betty A., Mains, Richard E.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096607/
https://ncbi.nlm.nih.gov/pubmed/17881726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-05-0503
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