Membrane-active Compounds Activate the Transcription Factors Pdr1 and Pdr3 Connecting Pleiotropic Drug Resistance and Membrane Lipid Homeostasis in Saccharomyces cerevisiae([Image: see text])

The Saccharomyces cerevisiae zinc cluster transcription factors Pdr1 and Pdr3 mediate general drug resistance to many cytotoxic substances also known as pleiotropic drug resistance (PDR). The regulatory mechanisms that activate Pdr1 and Pdr3 in response to the various xenobiotics are poorly understo...

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Hlavní autoři: Schüller, Christoph, Mamnun, Yasmine M., Wolfger, Hubert, Rockwell, Nathan, Thorner, Jeremy, Kuchler, Karl
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096591/
https://ncbi.nlm.nih.gov/pubmed/17881724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-06-0610
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