Conditionally lethal amber mutations in the leader peptidase gene of Escherichia coli.
The lep gene of Escherichia coli encodes the leader peptidase which cleaves amino-terminal leader sequences of secreted proteins. To facilitate the study of structure-function relationships of the leader peptidase, 22 amber mutations in lep were isolated by localized mutagenesis. These amber mutants...
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| Published in: | J Bacteriol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
1989
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209628/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2644209/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.171.1.585-587.1989 |
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