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Propagation and recovery of intact, infectious Epstein–Barr virus from prokaryotic to human cells

With current techniques, genetic alterations of herpesviruses are difficult to perform, mostly because of the large size of their genomes. To solve this problem, we have designed a system that allows the cloning of any γ-herpesvirus in Escherichia coli onto an F factor-derived plasmid. Immortalized...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Delecluse, Henri-Jacques, Hilsendegen, Tanja, Pich, Dagmar, Zeidler, Reinhard, Hammerschmidt, Wolfgang
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20961/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9653172/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.14.8245
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