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FLAG assay as a novel method for real-time signal generation during PCR: application to detection and genotyping of KRAS codon 12 mutations

Real-time signal generation methods for detection and characterization of low-abundance mutations in genomic DNA are powerful tools for cancer diagnosis and prognosis. Mutations in codon 12 of the oncogene KRAS, for example, are frequently found in several types of human cancers. We have developed a...

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Detalhes bibliográficos
Main Authors: Amicarelli, Giulia, Shehi, Erlet, Makrigiorgos, G. Mike, Adlerstein, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2095824/
https://ncbi.nlm.nih.gov/pubmed/17932053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm809
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