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Global control of aberrant splice-site activation by auxiliary splicing sequences: evidence for a gradient in exon and intron definition

Auxiliary splicing signals play a major role in the regulation of constitutive and alternative pre-mRNA splicing, but their relative importance in selection of mutation-induced cryptic or de novo splice sites is poorly understood. Here, we show that exonic sequences between authentic and aberrant sp...

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Autores principales: Královičová, Jana, Vořechovský, Igor
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2095810/
https://ncbi.nlm.nih.gov/pubmed/17881373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm680
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