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Biased exon/intron distribution of cryptic and de novo 3′ splice sites

We compiled sequences of previously published aberrant 3′ splice sites (3′ss) that were generated by mutations in human disease genes. Cryptic 3′ss, defined here as those resulting from a mutation of the 3′YAG consensus, were more frequent in exons than in introns. They clustered in ∼20 nt region ad...

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Autori principali: Královičová, Jana, Christensen, Mikkel B., Vořechovský, Igor
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1197134/
https://ncbi.nlm.nih.gov/pubmed/16141195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki811
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