Mutations in pattern recognition receptor genes modulate seroreactivity to microbial antigens in patients with inflammatory bowel disease

BACKGROUND AND AIMS: A number of antibodies against microbial epitopes or self‐antigens have been associated with Crohn's disease. The development of antibodies reflects a loss of tolerance to intestinal bacteria that underlies Crohn's disease, resulting in an exaggerated adaptive immune r...

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Autores principales: Henckaerts, Liesbet, Pierik, Marie, Joossens, Marie, Ferrante, Marc, Rutgeerts, Paul, Vermeire, Séverine
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Group 2007
Materias:
Inflammatory Bowel Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2095669/
https://ncbi.nlm.nih.gov/pubmed/17595233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2007.125468
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