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COX‐2 induction by unconjugated bile acids involves reactive oxygen species‐mediated signalling pathways in Barrett's oesophagus and oesophageal adenocarcinoma
OBJECTIVES: Bile reflux contributes to oesophageal injury and neoplasia. COX‐2 is involved in both inflammation and carcinogenesis; however, the precise mechanisms by which bile acids promote COX‐2 expression in the oesophagus are largely unknown. We analysed the molecular mechanisms that govern bil...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMJ Group
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2095641/ https://ncbi.nlm.nih.gov/pubmed/17604323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2007.121244 |
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