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Detection of BRAF V600E activating mutation in papillary thyroid carcinoma using PCR with allele‐specific fluorescent probe melting curve analysis
BACKGROUND: A single hotspot mutation at nucleotide 1799 of the BRAF gene has been identified as the most common genetic event in papillary thyroid carcinoma (PTC), with a prevalence of 29–83%. AIMS: To use a PCR assay to molecularly characterise the BRAF activating point mutation in a series of PTC...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BMJ Group
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2095462/ https://ncbi.nlm.nih.gov/pubmed/17298986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2006.040105 |
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