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Detection of BRAF V600E activating mutation in papillary thyroid carcinoma using PCR with allele‐specific fluorescent probe melting curve analysis

BACKGROUND: A single hotspot mutation at nucleotide 1799 of the BRAF gene has been identified as the most common genetic event in papillary thyroid carcinoma (PTC), with a prevalence of 29–83%. AIMS: To use a PCR assay to molecularly characterise the BRAF activating point mutation in a series of PTC...

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Detalhes bibliográficos
Main Authors: Rowe, Leslie R, Bentz, Brandon G, Bentz, Joel S
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2095462/
https://ncbi.nlm.nih.gov/pubmed/17298986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2006.040105
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