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CD4(+)CD28(–) costimulation-independent T cells in multiple sclerosis

Multiple lines of evidence suggest that CD4(+) lymphocytes initiate autoimmune responses against myelin antigens in multiple sclerosis (MS). The increased frequency of activated myelin-specific cells in MS patients indicates that the activation of autoreactive cells represents a central event in the...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Markovic-Plese, Silva, Cortese, Irene, Wandinger, Klaus-Peter, McFarland, Henry F., Martin, Roland
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2001
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209525/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11602626/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI12516
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