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Comparative potencies of 3,4-methylenedioxymethamphetamine (MDMA) analogues as inhibitors of [(3)H]noradrenaline and [(3)H]5-HT transport in mammalian cell lines

BACKGROUND AND PURPOSE: Illegal ‘ecstasy' tablets frequently contain 3,4-methylenedioxymethamphetamine (MDMA)-like compounds of unknown pharmacological activity. Since monoamine transporters are one of the primary targets of MDMA action in the brain, a number of MDMA analogues have been tested...

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Detalhes bibliográficos
Main Authors: Montgomery, T, Buon, C, Eibauer, S, Guiry, P J, Keenan, A K, McBean, G J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2095113/
https://ncbi.nlm.nih.gov/pubmed/17891159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707473
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