Retinoic acid prevents experimental Cushing syndrome

Cushing syndrome is caused by an excess of adrenocorticotropic hormone (ACTH) production by neuroendocrine tumors, which subsequently results in chronic glucocorticoid excess. We found that retinoic acid inhibits the transcriptional activity of AP-1 and the orphan receptors Nur77 and Nurr1 in ACTH-s...

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Detalhes bibliográficos
Main Authors: Páez-Pereda, Marcelo, Kovalovsky, Damian, Hopfner, Ursula, Theodoropoulou, Marily, Pagotto, Uberto, Uhl, Eberhard, Losa, Marco, Stalla, Johanna, Grübler, Yvonne, Missale, Cristina, Arzt, Eduardo, Stalla, Günter K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2001
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC209498/
https://ncbi.nlm.nih.gov/pubmed/11602619
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