Localization of tumor suppressor activity important in nonsmall cell lung carcinoma on chromosome 11q

Loss of heterozygosity on chromosome 11q23 is observed at high frequency in human nonsmall cell lung carcinomas (NSCLCs), suggesting the presence of a tumor suppressor gene. Previous analysis of DNA from 79 patients identified a commonly deleted segment of 5 centimorgans. Complementation analysis wa...

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Bibliographische Detailangaben
Hauptverfasser: Murakami, Yoshinori, Nobukuni, Takahiro, Tamura, Kenji, Maruyama, Tomoko, Sekiya, Takao, Arai, Yasuhito, Gomyou, Hiroki, Tanigami, Akira, Ohki, Misao, Cabin, Deborah, Frischmeyer, Pam, Hunt, Piper, Reeves, Roger H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1998
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC20945/
https://ncbi.nlm.nih.gov/pubmed/9653156
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