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X-deficient woodchuck hepatitis virus mutants behave like attenuated viruses and induce protective immunity in vivo

The X protein (HBX) of the hepatitis B virus (HBV) has been shown to be important for the establishment of HBV infection in vivo. Our previous studies suggested that interaction of HBX with the proteasome complex may underlie the pleiotropic functions of HBX. In this study, we generated a series of...

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Detalhes bibliográficos
Main Authors: Zhang, Zhensheng, Torii, Nobuyuki, Hu, Zongyi, Jacob, James, Liang, T. Jake
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC209423/
https://ncbi.nlm.nih.gov/pubmed/11714744
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