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X-deficient woodchuck hepatitis virus mutants behave like attenuated viruses and induce protective immunity in vivo

The X protein (HBX) of the hepatitis B virus (HBV) has been shown to be important for the establishment of HBV infection in vivo. Our previous studies suggested that interaction of HBX with the proteasome complex may underlie the pleiotropic functions of HBX. In this study, we generated a series of...

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Main Authors: Zhang, Zhensheng, Torii, Nobuyuki, Hu, Zongyi, Jacob, James, Liang, T. Jake
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC209423/
https://ncbi.nlm.nih.gov/pubmed/11714744
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